Manchester United will travel to Turkey to face former manager Jose Mourinho s Fenerbahce following the Europa League s revamped draw on Friday.
The new league phase format sees each of the 36 teams play eight games, four at home and four away.
During his two-and-a-half-year spell at United, Mourinho led them to Europa League glory in 2017, beating Ajax 2-0 in the final.
The Red Devils remaining seven games include an all-British home clash against Rangers, welcoming them to Old Trafford for the first time in 14 years, and a trip to another of Mourinho s old clubs, Porto.
Rangers, who have failed to win any of their last 13 games in major European competition against English opposition, will also face Tottenham and Conference League winners Olympiakos.
Spurs, winners of the inaugural tournament in 1972, will also meet Roma and Galatasaray in their other seven fixtures.
Home and away opponents for Pot 1 teams
— UEFA Europa League (@EuropaLeague)
Meanwhile, in the Conference League, Chelsea s draw includes League of Ireland side Shamrock Rovers at home and a trip to Panathinaikos.
The Blues, who narrowly qualified for the competition on Thursday, have never faced any of their six opponents in any competition before.